Welcome to 2425 Calle de Santiago--a rare opportunity to own a beautifully maintained home in the heart of historic Mesilla, NM. Just minutes from the iconic Mesilla Plaza, this 2-bedroom, 3-bath residence offers 2,241 sq ft of character-filled living space. Step into a warm foyer leading to a spacious living room with a wood-burning fireplace. The dining room connects seamlessly to the kitchen and sunken family room. A cozy den with wood stove, new evaporative cooler, ceiling fan, half bath, and extra storage links to the covered patio. Both full baths feature tile floors, vinyl countertops, and tub/shower combos, with a skylight in the hall bath. The kitchen includes new stainless steel appliances: dishwasher, electric range, vent hood. Enjoy the covered front and back patios, lush grass yards, and ample parking with a one-car carport and RV-accessible driveway for up to six vehicles. Built in 1982 on a 0.235-acre lot with a 2019 roof, this stucco home offers historic charm with modern updates.